The Kaslin group is interested in cellular plasticity in the brain and spinal cord. In particular the group is interested in how the neural system can repair itself by mobilising stem cells and how one can improve this process.
In the past, neural stem cells and brain regeneration has mostly been studied in vertebrates (such as rodents). The problem with this is that these vertebrates have very limited potential to regenerate.
Enter the zebrafish. This fish is able to regenerate parts of their central nervous system, even in adults. Using the zebrafish model is therefore much more advantageous to research as it can answer questions that previously could not be answered.
We use the zebrafish model to reveal how neural stem cell populations are formed during development and how they can controlled to improve repair after injury or in disease.