Fabrice Jaffré obtained his PhD at the Sorbonne University in Paris, where he explored the function of serotonin receptors in pathological cardiac hypertrophy. Fabrice later joined Beth Israel Deaconess Medical Center, Harvard Medical School where he used hiPSCs to delineate the molecular mechanisms underlying hypertrophic cardiomyopathy in RASopathies. His work was supported by a Scientist Development Grant from the American Heart Association. Fabrice next moved to New York City where he started his independent Lab at the Weill Cornell Medical College.

Fabrice joined ARMI in September 2024, where his lab uses human iPSCs, cardiac directed differentiation, genome editing (CRISPR), multi-omics, 3D organoids and engineered heart tissues as developmental and disease models. Fabrice’s work is currently supported by the Additional Ventures Single Ventricle Research Fund Award.

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