Professor Nir Eynon

GROUP LEADER | PROFESSOR

nir.eynon@monash.edu

Biography

Nir is a Rebecca L. Cooper Fellow and a Group Leader at the Australian Regenerative Medicine Institute (ARMI), Monash University, Australia. He earned his PhD degree with high distinction in 2010 from Porto University, Portugal. His areas of expertise epigenetics, ageing and exercise, an area for which he won the Young Tall Poppy 2021 & the 2024 Australian Epigenetics Alliance Excellence in Research awards. His expertise has been recognised by being selected to the ARC College of Experts in 2023. He is a former NHMRC Investigator Fellow (2021-2025), NHMRC Career Development Fellow (2018-2021), and ARC DECRA Fellow (2014-2016). He was recently awarded Hevolution/Am Fed Aging Research New Investigator Fellowship in Aging Biology. He published 125 papers and focuses on the discovery of sex-specific molecular markers associated with exercise & healthy ageing. The Eynon lab uses a combination of wet-lab and bioinformatics analyses, with a particular focus on ‘omics’ datasets including DNA methylation, transcription factors, transcriptomics and proteomics.

Learn more about Professor Eynon’s research here: Eynon Group – Australian Regenerative Medicine Institute

Click here for a full list of publications on ORCID

Featured Publications

Authors	Title	Published In
Seale K, Horvath S, Teschendorff A, Eynon N, Voisin S.	Making sense of the aging methylome.	Nature Reviews Genetics, 23;10(585-605). 2022
Voisin S, Jacques M, Landen S, Harvey NR, Haupt LM, Griffiths LR, Gancheva S, Ouni M, Jähnert M, Ashton KJ, Coffey VG, Thompson JLM, Doering TM, Gabory A, Junien C, Caiazzo R, Verkindt H, Raverdy V, Pattou F, Froguel P, Craig JM, Blocquiaux S, Thomis M, Sharples AP, Schürmann A, Roden M, Horvath S, Eynon N.	Meta-analysis of genome-wide DNA methylation and integrative omics of age in human skeletal muscle.	Journal of Cachexia, Sarcopenia and Muscle, 12;4(1064-1078). 2021
Landen S, Jacques M, Hiam D, Alvarez-Romero J, Harvey NR, Haupt LM, Griffiths LR, Ashton KJ, Lamon S, Voisin S, Eynon N.	Skeletal muscle methylome and transcriptome integration reveals profound sex differences related to muscle function and substrate metabolism.	Clinical Epigenetics, 13;202. 2021
Voisin S, Harvey NR, Haupt LM, Griffiths LR, Ashton KJ, Coffey VG, Doering TM, Thompson JLM, Benedict C, Cedernaes J, Lindholm ME, Craig JM, Rowlands DS, Sharples AP, Horvath S, Eynon N.	An epigenetic clock for human skeletal muscle.	Journal of Cachexia, Sarcopenia and Muscle, 11;4(887-898). 2020
Jacques M, Kuang J, Bishop DJ, Yan X, Alvarez-Romero J, Munson F, Garnham A, Papadimitriou ID, Voisin S, Eynon N.	Mitochondrial respiration variability and simulations in human skeletal muscle: The Gene SMART study.	The FASEB Journal. 34;2(2978-2986). 2020
Voisin S, Jacques M, Lucia A, Bishop DJ, Eynon N.	Statistical considerations for exercise protocols aimed at measuring trainability.	Exercise and Sport Sciences Reviews. 47;1(37-45). 2019
Landen S, Voisin S, Craig JM, McGee SL, Lamon S, Eynon N.	Genetic and epigenetic sex-specific adaptations to endurance exercise.	Epigenetics. 14;6(523-535). 2019
Houweling PJ, Papadimitriou ID, Seto JT, Pérez LM, Del Coso J, North KN, Lucia A, Eynon N.	Is evolutionary loss our gain? The role of ACTN3 p.Arg577Ter (R577X) genotype in athletic performance, ageing and disease.	Human Mutation. 39;12(1774-1787). 2018
Willems SM, Wright DJ, Day FR, … Eynon N, … Wareham NJ, Scott RA, et al.	Large-scale GWAS identifies multiple loci for hand grip strength providing biological insights into muscular fitness.	Nature Communications, 8;1 2017
Papadimitriou ID, Lucia A, Pitsiladis YP, Pushkarev VP, Dyatlov DA, Orekhov EF, Artioli GG, Guilherme JPLF, Lancha AH, Ginevičienė V, Cieszczyk P, Maciejewska- Karlowska A, Sawczuk M, Muniesa CA, Kouvatsi A, Massidda M, Garton CMCF, Houweling PJ, Wang G, Austin K, Druzhevskaya AM, Astratenkova IV, Ahmetov II, Bishop DJ, North KN, Eynon N.	ACTN3 R577X and ACE I/D gene variants influence performance in elite sprinters: a multi-cohort study.	BMC Genomics, 17;1. 2016