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Innate immune system modulates the regeneration process
Mikaël Martino’s research paper, “Inhibition of IL-1R1/MyD88 signalling promotes mesenchymal stem cell-driven tissue regeneration,” discusses how the innate immune system modulates the regeneration process, focusing, in particular, on injury to bone tissue. See the Resources column to the right to view the full paper as a PDF.
The not-so-big BOP revolutionising stem cell harvesting
Did you know the human body needs to produce one million blood cells every second of every day to live? In patients with leukaemia, rapidly multiplying abnormal white blood cells outcompete healthy cells, leaving the body starved of oxygen and lacking immunity. Treatment for this disease includes chemotherapy that kill the leukaemia cells, but as […]
New way to harvest stem cells better for donors
For bone marrow transplantation, stem cells are routinely harvested from healthy donors and used to treat patients with cancers including leukaemia. Current harvesting methods take a long time and require injections of a growth factor to boost stem cell numbers. This often leads to side effects. The discovery, published today in Nature Communications , reduces […]
Mining for intestinal stem cells
(Image from left to right: Jose Polo (Co-corresponding), Helen Abud (Co-corresponding), Christian Nefzger (Co-First), Thierry Jarde (Co-First)) Like most organs, our gut is made out of many different cell types. In a normal state, these cells work together to enable normal gut function. However, the gut can be subjected to a variety of diseases that can […]
Opinion: You might find my research using monkeys abhorrent, but it could save your life
First appeared in The Guardian, by James Bourne, 1 March 2016 ‘The care and welfare of animals are of paramount concern to every researcher.’ Photograph: Graeme Robertson for the Guardian “… and what do you do for a living James?” Before answering this question I can predict a range of responses to my answer. Some people lean forward […]
NPJ Regenerative Medicine – open for submissions
ARMI strives for two key results for our effort: to create new knowledge in stem cell and regenerative research that can improve patients lives, and to share our discoveries with the world. With this in mind, ARMI has teamed up with Nature Publishing Group to publish a new journal: npj Regenerative Medicine, an open access journal, sharing […]
Meet Hakan from Team Berger
Australian Regenerative Medicine Institute, 5 February 2016 For many PhD students, writing a science review is like a rite of passage into the scientific community. This was no different for Hakan Tarakci, a fresh ARMI PhD student in Prof. Peter Currie’s Lab, under the supervision of Dr. Joe Berger. With Hakan’s scientific curiosity piqued, starting […]
New ARMI Director Announced: Professor Peter Currie to take the lead
Australian Regenerative Medicine Institute, 5 February 2016 After an extensive international search, Professor Peter Currie, current Deputy Head of ARMI has been appointed to the role of ARMI Director. Professor Currie received his Ph.D. from Syracuse University, New York, USA. He undertook postdoctoral training in zebrafish development at the Imperial Cancer Research Fund (now Cancer […]
Recipe for tissue repair a skin cell breakthrough
First appeared in the Herald Sun, 19 January 2016, by Brigid O’Connell MELBOURNE researchers have created the “recipe book” for turning skin cells into almost any other cell in the human body. The landmark finding from the international research project paves the way for growing whole organs from human cells, as well as fast-tracking cell regeneration treatments […]
Science Portraits: biologists – Phong Nguyen, developmental biologist
As published in Cosmos Magazine, a portrait of three young scientists, featuring ARMI’s Young Scientist Dr Phong Nguyen. Read below to discover a science portrait of his research career thus far, his work with zebrafish and blood stem cells, and the impact to hope for in the area of leukaemia. Phong Nguyen is studying blood stem […]